(R)-4-N-Cbz-piperazine-3-carboxylic acid methyl ester

(R)-4-N-Cbz-piperazine-3-carboxylic acid methyl ester - Names and Identifiers

Name	1-Benzyl 3-methyl (3R)-piperazine-1,3-dicarboxylate
Synonyms	Methyl (R)-4-N-Cbz-piperazine-3-carboxylate 1-Benzyl 3-methyl (3R)-piperazine-1,3-dicarboxylate 1-benzyl 3-Methyl (3R)-piperazine-1,3-dicarboxylate (R)-4-N-Cbz-piperazine-3-carboxylic acid methylester (R)-4-N-Cbz-Piperazine-2-carboxylic acid methylester (R)-4-N-Cbz-piperazine-3-carboxylic acid methyl ester (R)-4-N-Cbz-Piperazine-2-Carboxylic Acid Methyl Ester (R)-4-N-CBZ-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER-HCl (3R)-1,3-Piperazinedicarboxylic acid 3-methyl 1-(phenylmethyl) ester 1,3-Piperazinedicarboxylic acid, 3-methyl 1-(phenylmethyl) ester, (3R)-
CAS	405175-79-3
InChI	InChI=1/C14H18N2O4/c1-19-13(17)12-9-16(8-7-15-12)14(18)20-10-11-5-3-2-4-6-11/h2-6,12,15H,7-10H2,1H3/t12-/m1/s1

(R)-4-N-Cbz-piperazine-3-carboxylic acid methyl ester - Physico-chemical Properties

Molecular Formula	C14H18N2O4
Molar Mass	278.3
Density	1.212
Boling Point	406.5°C at 760 mmHg
Flash Point	199.7°C
Vapor Presure	8.08E-07mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.537

(R)-4-N-Cbz-piperazine-3-carboxylic acid methyl ester - Introduction

1-Benzyl 3-methyl (3R)-piperazine-1,3-dicarboxylate is an organic compound with the chemical formula C21H24N2O4.

Nature:
1-Benzyl 3-methyl (3R)-piperazine-1,3-dicarboxylate is a solid crystal with a white or off-white color. It is stable at room temperature and soluble in some non-polar solvents such as dichloromethane, ethanol and dimethyl sulfoxide.

Use:
1-Benzyl 3-methyl (3R)-piperazine-1,3-dicarboxylate is an organic synthesis intermediate commonly used in drug synthesis and chemical reactions. Its presence can control the amine group in piperazine through the process of protection and deprotection, so it plays an important role in drug design and synthesis.

Preparation Method:
The preparation of 1-Benzyl 3-methyl (3R)-piperazine-1,3-dicarboxylate can usually be obtained by reacting piperazine with methyl formylformate under alkaline conditions.

Safety Information:
The specific safety information for 1-Benzyl 3-methyl (3R)-piperazine-1,3-dicarboxylate is unclear. As a chemical, its use should comply with the relevant safety procedures and protective measures. During use, care should be taken to avoid contact with skin and eyes, and to prevent inhalation and ingestion. Seek immediate medical help if exposed or ingested.

Last Update：2024-04-09 15:17:57